Ovalbumin (OVA) mRNA (5moU) is a synthetic messenger RNA encoding the ovalbumin protein, the predominant glycoprotein found in egg whites. This mRNA is optimized for high expression levels and incorporates N1-methylpseudouridine (5moU) modifications to enhance translation efficiency and reduce immunogenicity. It is capped with a Cap-1 structure and includes a poly(A) tail, mimicking fully processed mature mRNA. OVA mRNA (5moU) serves as an excellent tool for immunology research, vaccine development, and studies involving antigen presentation and immune responses.

WARNING: This product is not for human or veterinary use.

Available QC Assays

Concentration	Standard, UV-Vis
A260/280	Standard, UV-Vis
Integrity	Standard, Fragment Analysis by Capillary Electrophoresis
Appearance	Standard
Endotoxin	Standard, < 10EU/mg
Purity	IP-RP-HPLC
RNA Aggregation Assay	SEC-HPLC
DNA Sequencing	Sanger Sequencing
dsRNA Content	ELISA

OVA mRNA (5moU)

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OVA mRNA (5moU) is a synthetic messenger RNA encoding Ovalbumin (OVA), a widely studied model antigen derived from Gallus gallus (chicken egg white). This mRNA is designed for high-efficiency translation in mammalian cells and is widely used in immunology research, antigen presentation studies, vaccine development, and cancer immunotherapy.

Our OVA RNA product is designed to provide researchers with a high-quality and reliable source of this critical tool for their experiments. For research use-only.

Description

Product Name	Ovalbumin (OVA) mRNA
Length	1450 nt
Modifications	5-Methoxyuridine (5moU)
Appearance	Clear, Colorless Solution
Buffer	1mM Sodium Citrate, pH 6.4
Purity	>90%, Fragment analysis by capillary gel electrophoresis
Concentration	~1 mg/mL
A260/280	~2.0
Endotoxin	<10 EU/mg
Storage	≤ -40°C
Shipping Method	Dry Ice

Immunotherapy Research: Used as a model antigen for developing mRNA-based cancer vaccines.

Antigen Presentation Studies: Investigates MHC-I and MHC-II antigen presentation pathways in dendritic cells and T-cell activation.

In Vivo and In Vitro Studies: Evaluates mRNA delivery, expression kinetics, and immune response in preclinical models.

Cell Transfection & mRNA-LNP Formulation: Compatible with lipid nanoparticles (LNPs) for efficient delivery in cells and animal models.

OVA mRNA (5moU)

Technical Specifications

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