Cre mRNA (N1MePU) is fused to the SV40 nuclear localization sequeence (NLS) for superior nucleus expression.

Cre mRNA is a powerful tool for genetic recombination, enabling precise modifications to be made to the genetic code of cells and organisms.

WARNING: This product is not for human or veterinary use.

Available QC Assays

Concentration	Standard, UV-Vis
A260/280	Standard, UV-Vis
Integrity	Standard, Fragment Analysis by Capillary Electrophoresis
Appearance	Standard
Endotoxin	Standard, < 10EU/mg
Purity	IP-RP-HPLC
RNA Aggregation Assay	SEC-HPLC
DNA Sequencing	Sanger Sequencing
dsRNA Content	ELISA

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Product Citations

1. Aishwarya Vasudevan, ... Gaurav Sahay et al. "Lipid nanoparticle-mediated intracameral mRNA delivery facilitates gene expression and editing in the anterior chamber of the eye." Journal of Controlled Release, 379, 1022–1028. 2025.

Cre mRNA (N1MePU)

From $200.00

Quantity

This RNA encodes Cre recombinase enzyme, a powerful tool for genetic recombination. Our Cre RNA product is designed to provide researchers with a high-quality and reliable source of this critical tool for their experiments.

Description

Product Name	NLS-Cre (Cre) mRNA
Length	1352 nt
Modifications	N1-methyl-pseudouridine (N1MePU)
Appearance	Clear, Colorless Solution
Buffer	1mM Sodium Citrate, pH 6.4
Purity	>90%, Fragment analysis by capillary gel electrophoresis
Concentration	~1 mg/mL
A260/280	~2.0
Endotoxin	<10 EU/mg
Storage	≤ -40°C
Shipping Method	Dry Ice

Conditional gene knockout

Cre RNA is commonly used to generate conditional knockout mice, enabling the study of gene function in specific tissues or at specific developmental stages.

Genetic lineage tracing

Cre RNA can be used to track the lineage of cells during development or in disease models.

Genome engineering

Cre RNA can be used for site-specific integration of transgenes or other genetic elements.

Cre mRNA (N1MePU)

Technical Specifications

Applications

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