Cre mRNA (N1MePU) is fused to the SV40 nuclear localization sequeence (NLS) for superior nucleus expression.
Cre mRNA is a powerful tool for genetic recombination, enabling precise modifications to be made to the genetic code of cells and organisms.
WARNING: This product is not for human or veterinary use.
Available QC Assays
Concentration | Standard, UV-Vis |
| A260/280 | Standard, UV-Vis |
| Integrity | Standard, Fragment Analysis by Capillary Electrophoresis |
| Appearance | Standard |
| Endotoxin | Standard, < 10EU/mg |
| Purity | IP-RP-HPLC |
| RNA Aggregation Assay | SEC-HPLC |
| DNA Sequencing | Sanger Sequencing |
| dsRNA Content | ELISA |
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Product Citations
1. Aishwarya Vasudevan, ... Gaurav Sahay et al. "Lipid nanoparticle-mediated intracameral mRNA delivery facilitates gene expression and editing in the anterior chamber of the eye." Journal of Controlled Release, 379, 1022–1028. 2025.
Cre mRNA (N1MePU)
This RNA encodes Cre recombinase enzyme, a powerful tool for genetic recombination. Our Cre RNA product is designed to provide researchers with a high-quality and reliable source of this critical tool for their experiments.
Description
Product Name
NLS-Cre (Cre) mRNA Length 1352 nt Modifications N1-methyl-pseudouridine (N1MePU) Appearance Clear, Colorless Solution Buffer 1mM Sodium Citrate, pH 6.4 Purity >90%, Fragment analysis by capillary gel electrophoresis Concentration ~1 mg/mL A260/280 ~2.0 Endotoxin <10 EU/mg Storage ≤ -40°C Shipping Method Dry Ice Conditional gene knockout
- Cre RNA is commonly used to generate conditional knockout mice, enabling the study of gene function in specific tissues or at specific developmental stages.
Genetic lineage tracing
- Cre RNA can be used to track the lineage of cells during development or in disease models.
Genome engineering
- Cre RNA can be used for site-specific integration of transgenes or other genetic elements.