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StrandSolve

mRNA Sequence Optimizer

From Sequence to Lead

Partner with Helix Biotech

We believe great therapeutics begin with great RNA. Our proprietary sequence optimization engine, StrandSolve™, is built to help you unlock the full potential of your mRNA programs, whether you're developing vaccines, protein replacement therapies, or gene editing tools.

Full-Transcript Engineering: We go beyond codon optimization. StrandSolve™ simultaneously optimizes 5’ UTRs, coding regions, and 3’ UTRs for maximum translational efficiency and stability.
 

Seamless Integration: We pair StrandSolve™ with our mRNA synthesis and LNP formulation services to generate lead candidates in no time.

Unlocking mRNA's Full Potential

"One Protein. Innumerable mRNAs."
Not all mRNAs are created equal. StrandSolve™ finds those that performs best.

Unoptimized mRNA leads to low expression, immunogenicity, and wasted time

Traditional codon optimization is insufficient

Better design = higher & longer expression,
faster development,
fewer failures

Holistic Approach to mRNA Design

Sequence design beyond codon frequency

Five Rectangle Flow Diagram Graph.png

Is your mRNA provider considering these factors?

Liquid Bubbles

Submit an mRNA Inquiry Form

mRNA Information

Gene Synthesis by Helix Biotech
Codon Optimization
5' and 3' UTRs Provided in Sequence Below?
5' Cap
PolyA Tail
Modifications
Desired Buffer
Quality Control
Abstract DNA Strand

High-Purity Custom mRNA for Your Research

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