EZNano™ LNP Formulation Buffers from Helix Biotech is a ready‑to‑use acidic buffer optimized for forming high‑quality lipid nanoparticles (LNP) with RNA and other nucleic acid cargos. This solution maintains a controlled pH to promote efficient complexation between ionizable lipids and nucleic acids during the mixing step.
 
Simply dilute your mRNA or DNA with the LNP Formulation Buffer and mix with your lipid mixture to generate LNP formulations.
 
A 1 M concentrate is available for advanced formulation workflows recuiring custom buffer preparation or high-concentration RNA stock solutions. 
 
For assistance with RNA stock solution preparation and buffer mixing calculations, see our LNP Formulation Calculator. 
 
*Larger volumes and GMP-grade material available upon request.