Most RNA Programs Fail
For Two Predictable Reasons
We Solve Both.
THE RNA CONSTRUCT
Weak constructs kill programs before they can reach the clinic.
THE DELIVERY SYSTEM
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Unscalable, unlicensable, unreproducible nanoparticles stall programs.
Here's how we solve it
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Beyond Just Simple Codon Optimization
Our StrandSolve™ platform designs RNA constructs for peak performance, integrating sequence optimization with structural, stability, and manufacturability insights to promote expression while minimizing unwanted interactions.
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Helix Biotech enables:
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Rational RNA sequence optimization for expression and stability
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Design with manufacturability in mind
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Iterative testing and rapid feedback loops
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Reduced redevelopment risk between research and clinical material
One Integrated Pathway
Manufacturing Platforms and Services
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Controlled mixing dynamics at multiple scales
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Reproducible particle size and encapsulation efficiency
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Lipid nanoparticles (LNPs), Liposomes, PLGa, Polymer nanoparticles, lipoplexes, microbubbles and more.
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Manufacturing pathways designed for R&D to clinical and commercial
We are experts in formulation optimization, process development, analytical support, scale up, and GMP manufacturing.​​ Our NOVA™ IJM platform is built around turbulent mixing principles that allow controlled, scalable nanoparticle formation.
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The NOVA™ IJM enables:
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Trusted by Scientists
Mathew Sebastiao, PhD
Glycovax Pharma
On implementing the Nova: "One thing that we definitely appreciate is the excellent yield we are getting due to not having to extrude the vesicles. I was dealing with up to 20% material loss simply from the repeatedly clogged membranes! Now the production is essentially quantitative and any "waste" is easily recovered."
Eziz Kuliyev, PhD
Reprogram Biosciences
"Working with the Helix Biotech team has made a meaningful difference for us. Their deep technical expertise across mRNA design, delivery, and manufacturing has helped us make the right design choices early and avoid unnecessary iteration."
Dan Peer, PhD
Tel Aviv University
On using the Nova: "You do not need to use chips per each preparation, the system is robust and excellent for both beginners and advanced researchers in the field. Just plug and play."
Products
From mRNA and lipid reagents to LNP manufacturing systems, Helix Biotech has everything you need to complete your project
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