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  • Michael Nguyen

What is Turbulent Mixing?

Updated: Apr 23

Turbulent Mixing refers to the process of rapidly combining substances using turbulence to enhance the mixing efficiency. Turbulence is a state of fluid flow characterized by chaotic, stochastic property changes. This includes low momentum diffusion, high momentum convection, and rapid variation of pressure and velocity in space and time.

Importance in Lipid Nanoparticle (LNP) Production

In the context of LNP production, turbulent mixing is particularly valuable due to its ability to rapidly and uniformly mix the lipid and aqueous phases necessary for the formation of these nanoparticles. Here’s why it’s beneficial:

  • Speed: Turbulent mixing allows for the rapid formation of LNPs, which is crucial for encapsulating molecules that might be unstable or prone to degradation over time.

  • Efficiency: The intense mixing action ensures that the encapsulation of therapeutic agents, such as mRNA or other drugs, is both efficient and consistent, leading to LNPs with uniform size and composition.

  • Scalability: Turbulent mixing methods can be easily scaled up to meet industrial production demands without losing effectiveness, making it suitable for large-scale pharmaceutical manufacturing.

Discover More with Helix Biotech, Inc.

Interested in exploring how our Nova™ IJM nanoparticle manufacturing system can help you? Visit our dedicated Nova products page to learn how Helix Biotech, Inc. can assist you in starting your own LNP projects. Learn more about our solutions and get started today!


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