GMP Manufacturing
At Helix Biotech, we've developed our own manufacturing platform to quickly and reliably screen nanoparticle formulations, such as lipid nanoparticles (LNP), liposomes, emulsions, and polymer-based particles.
Leadtimes as low as 2 weeks
How we decrease LNP leadtimes
1) We synthesize and acquire high quality mRNA and lipid reagents to lower acquisition time.
2) We've innovated an automated manufacturing platform (i.e. the Nova™ IJM) to streamline nanoparticle production for a wide sample volume range (microliter to liter scale).
Selecting the Right Nanoparticle Formulation
Our team of scientists select from a catalogue of well known standard lipid- or polymer-based formulations, sourced from our partners and suppliers, to optimize the encapsulation, targeted delivery, and expression of your API.
Optimization by Design of Experiments (DOE) - Our experts apply the Design of Experiments concept to help optimize your formulation, improve your delivery system and therapeutics, and accelerate your project success.
We help identify key variables that have the greatest impact on formulation stability and efficacy, and determine the optimal parameters to achieve your goals.
LNP Expertise in GMP Manufacturing and Scale Up
Even during the screening stage, we have a pathway to scaling up your manufacturing. Our expertise is in designing manufacturing systems and in GMP manufacturing of drug products which helps us streamline your development process.
We will help you design the optimal system to increase output and keep reagent, analytical, and FTE costs at a minimum.